Monthly Archives: August 2012

Longitudinal diffusion tensor imaging and neuropsychological correlates in traumatic brain injury patients

The results of this study showing progressive WM deterioration for several years post-injury contribute to a growing literature supporting the hypothesis that TBI should be viewed not as an isolated incident but as a prolonged disease state. Read article

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Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

Following the primary mechanical insult TBI results in delayed secondary injury events due to neurochemical, metabolic and cellular changes that account for many of the neurological deficits observed after TBI. Read article

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Complexity of intracranial pressure correlates with outcome after traumatic brain injury

The complexity of intracranial pressure assessed by multiscale entropy was significantly associated with outcome in patients with brain injury. Read article

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Neuropsychological assessment of distractibility in mild traumatic brain injury and depression

Significant improvement of performance in the distraction setting was documented for clients with MDE. Read article

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Depression, anxiety, and stress as predictors of postconcussion-like symptoms in a non-clinical sample

Results suggest that stress may be a more important predictor of postconcussion-like symptoms than previously identified. Read article

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Association between posttraumatic stress, depression, and functional impairments in adolescents 24 months after traumatic brain injury

Results indicated that patients who sustained a mild TBI without intracranial hemorrhage reported significantly worse PTSD (Hedges g = 0.49, p = .01; Model R(2) = .38) symptoms across time as compared to the arm injured control group. Greater levels … Continue reading

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Abnormal whole-brain functional networks in homogeneous acute mild traumatic brain injury

Whole-brain functional connectivity is altered early (within 4 weeks) after MTBI, suggesting that changes in functional networks underlie the cognitive deficits and postconcussive complaints reported by patients with MTBI. Read article

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Dementia resulting from traumatic brain injury: What is the pathology?

It is presently unknown whether dementia in TBI survivors is pathophysiologically similar to Alzheimer disease, CTE, or some other entity. Read article

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Diffusion tensor imaging studies of mild traumatic brain injury

Meta-analysis revealed the posterior part of the CC was more vulnerable to mTBI compared with the anterior part, and suggested the potential utility of DTI to detect white matter damage in the CC of mTBI patients. Read article

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Working memory in patients with mild traumatic brain injury

MTBI-induced differences in working memory functional activity were observed even though differences in behavioral performance between MTBI patients and controls were absent, which suggests that this approach may increase sensitivity to MTBI compared with neuropsychological evaluation alone. Read article

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